Thoughts
On tech, AI, business, and what actually works.
August 10, 2026
DNA was isolated in 1869 from pus-soaked surgical bandages, proved to carry heredity in 1944 by a paper the field refused to believe, and finally given a shape in 1953 — a discovery whose credit is still being relitigated in the archives.
June 26, 2026
At Göbekli Tepe and the cluster of "Stone Hills" sites in southeastern Turkey, hunter-gatherers raised the world's oldest monuments some 11,500 years ago — before farming, pottery, or the wheel. The discoveries overturned a century-old assumption that agriculture had to come first, and suggest civilization may have begun not with the plow, but with the temple.
June 22, 2026
The protein-structure revolution that won AlphaFold a Nobel Prize has quietly split into three races — prediction, design, and medicine. A field guide to the top contenders (AlphaFold 3, Boltz, Chai, RFdiffusion, ESM3, Isomorphic Labs) and the one tension none of them has resolved: the benchmarks have never looked better, and not a single AI-designed drug has yet been approved.